Running Man must find the two guests among many masked people before the guests find Running Balls that eliminate 2 Running Man members at a time. A drawing relay takes place after, and then they undergo a choreography dance challenge which if they pass will result in no punishment for anyone.
For this week, the Running Man members go on a vacation. However, not only is it a vacation, but it is an 'Unlucky Vacation'. The members are divided into two teams, and among them, the unlucky ones and the lucky ones partner up. Every time a team wins, they receive one point and also the right to pick a penalty for the losing team. Will the lucky members be able to live up to their name? Or will the unlucky members regain their honor?
This week's race is called Dangerous Invitation that will unite ghosts from the East and West. With Son Na Eun, Seo Young Hee, and Ahn Hyo Seop joining as guests, the members show up wearing different costumes and makeups of famous characters from dramas and movies to celebrate Halloween. Then, the members and guests are divided into two teams, Team Humans and Team Ghosts, and play three missions. Winning members receive a hint that will lead them to win this week's race. Stay tuned to find out the ultimate winner.
Special events for So Min's birthday continue. After having a meal at a fancy restaurant, So Min and Ji Suk move on to learn how to dance the tango. And another man is expecting So Min to come there. Meanwhile, the other Running Man members are busy solving the quizzes and completing missions as fast as they can to catch So Min.
This week, the members develop the ideas about the presents that they'll be giving out to their fans at the fan-meet that will be held in about two months. Also, they start to practice a group dance performance that they will put on at the fan-meet. To teach dance to the members, a famous instructor joins the show.
The members continue to work on the t-shirt that they will give out to their fans at the fan-meet. Whose drawings will be printed on the t-shirt? Also, the members keep practicing the group dance moves with Lia, the choreographer. But they soon get exhausted and frustrated with the extremely challenging choreography.
This week, Ong Seong Wu, Lee Do Hyun, Seo Ji Hun, and ZICO team up with Kwang Soo to form Team Good-looking. They take on the Team of Entertainers led by Seok Jin for R coins. It's a team effort for the win, but betrayal within the teams gets tempers flared with an unexpected end to the race.
This week, six guests join the members to continue the race to win as much money as they can. The guests are Soyou, Kim Dong Jun, Jang Won Young, Kim Do Yeon, Lee Mi Joo, and YUQI. They partner up with the members and carry out the missions to win the prize and prize money. The team that comes in last receives a penalty.